Jinjuan Liu
Telephone: 15190666989
E-mail: jjlbest@jsnu.edu.cn
Education
Ph.D., China Pharmaceutical University, 2010
M.S., Guizhou University, 2007
B.S., Jiangsu Normal University, 2004
Research Experience
Aug. 2010 - present, Jiangsu Normal University, Lecturer, Associate professor
Aug. 2010 - Aug. 2018, Jiangsu Normal University, Lecturer
Feb. 2014 -Aug. 2014, University of Edinburgh, visiting scholar
Research Interests
1.Antitumor efficacy and molecular mechanism of natural products
2.Molecular mechanism of protective agents against oxidative damage
Research projects
1.The molecular mechanism of natural novel 2-animomethyl-actinomycin D inducing hepatocellular carcinoma cell apoptosis by down-regulating mtTFA, The National Foundation of Natural Science No.81603150, 2017.1-2019.12.
2.The molecular mechanism and biological effects of natural novel actinomycin D on down regulation of mtTFA. Natural Science Fund project in Jiangsu Province No.BK20160222, 2016.7-2019.6.
3.Study on anti-tumor mechanism of cordate houttuynia extraction，Doctoral research foundation of Jiangsu Normal University No.10XLR25, 2011.1-2012.12.
4.Antitumor effects of novel actinomycin D derivatives and their mechanisms，Natural science fund for colleges and universities in Jiangsu Province, No.11KJB310011, 2011.09-2013.09.
Publications
[1]Yong-Qiang Chen, Jin-Juan Liu (co-author), Bo Yuan, Cheng-Liang Cao, Sheng-Qin, Xiao-Ying Cao, Guang-Kai Bian, Zhe Wang, Ji-Hong Jiang* Methylated actinomycin D, a novel actinomycin D analog induces apoptosis in HepG2 cells through Fas- and mitochondria-mediated pathways. Molecular Carcinogenesis. 52(12):983-996. 2013.
[2]Shou-Hui Yang, Jin-Juan Liu (co-author), Yong-Qiang Chen, Ji-Hong Jiang* Reversal effect of Tween-20 on multidrug resistance in tumor cells in vitro. Biomed Pharmacother. 66(3):187-94. 2012.
[3]Jin-Juan Liu, Xiang Ma, Ling-Bo Cai, Yu-Gui Cui, Jia-Yin Liu* Downregulation of both gene expression and activity of Hsp27 improved maturation of mouse oocyte in vitro. Reproductive biology and endocrinology. 47(8):1-12. 2010.
[4]Jin-Juan Liu, Xue-Qin Ran, Sheng Li, Ya-li Feng, Jia-Fu Wang* Polymorphism in the first intron of follicle stimulating hormone beta gene in three Chinese pig breeds and two European pig breeds. Animal Reproduction Science. 111:369-375. 2009.